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Covalent hitchhikers guide proteins to the nucleus

Alexander F Russell1, Madeline F Currie1, Champak Chatterjee1

  • 1Department of Chemistry, University of Washington, Seattle, WA 98195, USA.

Cell Chemical Biology
|March 22, 2024
PubMed
Summary

Researchers combined chemoproteomics and proximity labeling to find reactive cysteines in nuclear proteins. This novel method identified proteins localized to the nucleus and chromatin after probe labeling.

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