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Immune tolerance induction by hepatic gene transfer: First-in-human evidence

Radoslaw Kaczmarek1, Benjamin J Samelson-Jones2, Roland W Herzog1

  • 1Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|March 22, 2024
PubMed
Abstract

No abstract available in PubMed .

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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