Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Asepsis01:28

Asepsis

2.1K
The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
2.1K
Surface Membrane Barriers01:18

Surface Membrane Barriers

1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Hand hygiene01:23

Hand hygiene

3.2K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
3.2K
Infection01:20

Infection

7.9K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A pilot randomized clinical trial evaluating the feasibility, acceptability, and preliminary efficacy of a cognitive-behavioral therapy adjunct to support benzodiazepine tapering among primary care patients coprescribed benzodiazepines and opioids.

Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors·2026
Same author

Ketogenic diet synergistic reprogramming of both host and microbiome promotes tissue regeneration.

bioRxiv : the preprint server for biology·2026
Same author

Cryo-EM analysis of the Staphylococcus aureus phenol-soluble modulin exporter PmtCD apo form in detergent micelles, nanodiscs and peptidiscs.

Communications biology·2025
Same author

Host DNA damage and cellular fate in bacterial infections, with a focus on Staphylococcus aureus.

FEMS microbiology reviews·2025
Same author

Quorum-sensing control of sepsis in the coagulase-negative staphylococcal species Staphylococcus haemolyticus.

Cell reports·2025
Same author

Nasal Staphylococcus aureus carriage promotes depressive behaviour in mice via sex hormone degradation.

Nature microbiology·2025

Related Experiment Video

Updated: Jun 30, 2025

Improved Enzyme Protection Assay to Study Staphylococcus aureus Internalization and Intracellular Efficacy of Antimicrobial Compounds
06:36

Improved Enzyme Protection Assay to Study Staphylococcus aureus Internalization and Intracellular Efficacy of Antimicrobial Compounds

Published on: September 8, 2021

2.8K

Staphylococcus aureus colonisation and strategies for decolonisation.

Pipat Piewngam1, Michael Otto1

  • 1Pathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, MD, USA.

The Lancet. Microbe
|March 22, 2024
PubMed
Summary
This summary is machine-generated.

Staphylococcus aureus infections are a major global health threat. New strategies, including probiotics targeting intestinal colonization, are needed to prevent infections as antibiotic resistance rises.

More Related Videos

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
08:32

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

454
Deferred Growth Inhibition Assay to Quantify the Effect of Bacteria-derived Antimicrobials on Competition
07:42

Deferred Growth Inhibition Assay to Quantify the Effect of Bacteria-derived Antimicrobials on Competition

Published on: September 3, 2016

14.6K

Related Experiment Videos

Last Updated: Jun 30, 2025

Improved Enzyme Protection Assay to Study Staphylococcus aureus Internalization and Intracellular Efficacy of Antimicrobial Compounds
06:36

Improved Enzyme Protection Assay to Study Staphylococcus aureus Internalization and Intracellular Efficacy of Antimicrobial Compounds

Published on: September 8, 2021

2.8K
Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
08:32

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

454
Deferred Growth Inhibition Assay to Quantify the Effect of Bacteria-derived Antimicrobials on Competition
07:42

Deferred Growth Inhibition Assay to Quantify the Effect of Bacteria-derived Antimicrobials on Competition

Published on: September 3, 2016

14.6K

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Staphylococcus aureus is a major cause of infectious disease deaths globally.
  • Antibiotic resistance complicates treatment, necessitating infection prevention strategies.
  • Asymptomatic colonization is a primary source of S. aureus infections.

Purpose of the Study:

  • To review the epidemiology and mechanisms of S. aureus colonization.
  • To discuss current and novel decolonization approaches.
  • To highlight probiotic strategies and intestinal colonization.

Main Methods:

  • Literature review of S. aureus colonization and infection.
  • Analysis of current decolonization methods (antibiotic and antiseptic).
  • Examination of emerging probiotic strategies and intestinal S. aureus sites.

Main Results:

  • S. aureus colonization precedes most infections.
  • Existing decolonization methods show limitations and rising resistance.
  • Probiotic strategies offer a promising alternative for decolonization.

Conclusions:

  • Effective prevention of S. aureus infections relies on successful decolonization.
  • Novel approaches, particularly those targeting intestinal colonization with probiotics, are crucial.
  • Addressing antibiotic resistance requires innovative decolonization strategies.