Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
  1. Home
  3. Research Domains
  1. Home
  3. Research Domains

Related Concept Videos

  • Biomedical And Clinical Sciences
  • Oncology And Carcinogenesis
  • Predictive And Prognostic Markers
  • Survival Outcomes Of Surgical Resection In Perihilar Cholangiocarcinoma In Endemic Area Of O. Viverrini, Northeast Thailand.
  • Biomedical And Clinical Sciences
  • Oncology And Carcinogenesis
  • Predictive And Prognostic Markers
  • Survival Outcomes Of Surgical Resection In Perihilar Cholangiocarcinoma In Endemic Area Of O. Viverrini, Northeast Thailand.

    • Related Experiment Video

    Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
    04:50

    Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

    Published on: January 17, 2025

    209

    Survival outcomes of surgical resection in perihilar cholangiocarcinoma in endemic area of O. Viverrini, Northeast Thailand.

    Poowanai Sarkhampee1, Sunhawit Junrungsee2, Apichat Tantraworasin2

    • 1Department of Surgery, Sunpasitthiprasong Hospital, Ubon Ratchathani, Thailand.

    Asian Journal of Surgery
    |March 22, 2024

    View abstract on PubMed

    Summary
    This summary is machine-generated.

    Surgical resection significantly improves survival outcomes for patients with perihilar cholangiocarcinoma (pCCA). Key factors impacting long-term survival include Bismuth type, resection margin status, and lymph node metastasis.

    Keywords:
    CholangiocarcinomaO.ViverriniPerihilar cholangiocarcinomaSurgical resectionSurvival outcomes

    More Related Videos

    Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
    07:22

    Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

    Published on: April 11, 2025

    137
    Robotic Taj Mahal Hepatectomy for Hilar Cholangiocarcinoma
    09:19

    Robotic Taj Mahal Hepatectomy for Hilar Cholangiocarcinoma

    Published on: July 14, 2022

    3.4K

    Related Experiment Videos

    Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
    04:50

    Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

    Published on: January 17, 2025

    209
    Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
    07:22

    Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

    Published on: April 11, 2025

    137
    Robotic Taj Mahal Hepatectomy for Hilar Cholangiocarcinoma
    09:19

    Robotic Taj Mahal Hepatectomy for Hilar Cholangiocarcinoma

    Published on: July 14, 2022

    3.4K

    Area of Science:

    • Hepatobiliary Surgery
    • Surgical Oncology
    • Gastroenterology

    Background:

    • Perihilar cholangiocarcinoma (pCCA) is a challenging malignancy with poor prognosis.
    • Surgical intervention is a primary treatment modality, but outcomes vary significantly.

    Purpose of the Study:

    • To evaluate survival outcomes in patients with pCCA.
    • To identify prognostic factors influencing long-term survival after surgical exploration.

    Main Methods:

    • Retrospective review of 240 consecutive pCCA patients undergoing surgical exploration (October 2013 - December 2018).
    • Comparison of survival between resectable and unresectable groups using restricted mean survival time (RMST).
    • Multivariable Cox regression analysis to identify independent predictors of survival in the resectable group.

    Main Results:

    • Surgical resection was performed in 83.75% of patients, with significantly better survival in the resectable group (RMST differences ranging from 0.5 to 9.1 months at landmark time points).
    • Major complications and 90-day mortality in the resectable group were 35.82% and 11.44%, respectively.
    • Independent predictors of poor long-term survival included Bismuth type IV, positive resection margin, and lymph node metastasis (p < 0.001).

    Conclusions:

    • Surgical resection is associated with improved survival for pCCA patients.
    • Bismuth type IV, positive resection margins, and lymph node metastasis are critical independent prognostic factors for long-term survival in pCCA.