Related Experiment Video
Updated: Jun 30, 2025

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
Multidisciplinary Consensus on the Management of Non-Invasive Respiratory Support in the COVID-19 Patient
Manel Luján1, César Cinesi Gómez2, Oscar Peñuelas3
1Servei de Pneumologia, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Universitat Autònoma de Barcelona, Sabadell, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
This study provides evidence-based recommendations for managing severe COVID-19 respiratory failure, focusing on non-invasive support to avoid intubation. It addresses critical clinical and organizational issues for optimal patient care and healthcare worker safety.
Area of Science:
- Critical Care Medicine
- Pulmonology
- Infectious Diseases
Background:
- COVID-19 pneumonia frequently causes acute respiratory failure, necessitating strategies to prevent endotracheal intubation.
- Non-pharmacological interventions, including non-invasive support and awake proning, are crucial components of care.
- Early guidelines relied on acute respiratory distress syndrome experience, but evolving evidence now informs COVID-19 specific management.
Purpose of the Study:
- To synthesize current evidence and expert consensus for managing severe COVID-19 respiratory failure.
- To provide recommendations on initiating and selecting non-invasive support modalities.
- To outline criteria for treatment failure, de-escalation, and organizational considerations.
Main Methods:
- Collaborative effort involving four leading scientific societies (SEDAR, SEMES, SEMICYUC, SEPAR).
- Involved 25 experts in critical care and respiratory medicine.
- Synthesized high-quality studies and expert experience to address clinical questions.
Main Results:
- Established evidence-based recommendations for non-invasive support in COVID-19.
- Defined optimal timing, modality selection, and failure criteria for respiratory support.
- Addressed organizational aspects and healthcare worker protection during aerosol-generating procedures.
Conclusions:
- Comprehensive, evidence-based strategies are essential for managing severe COVID-19 respiratory failure.
- Optimizing non-invasive support and patient monitoring improves outcomes and avoids intubation.
- Expert consensus refines patient care and addresses challenges in severe COVID-19 infection.
Related Concept Videos
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment
COPD: Management Using Bronchodilators and Corticosteroids
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....

