Intraoperative visualization of cranial nerve schwannomas using second-window indocyanine green: A case series
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View abstract on PubMed
Summary
This summary is machine-generated.Second Window Indocyanine Green (SWIG) imaging effectively visualized cranial nerve schwannomas, enabling successful tumor resection. This technique shows promise for improving surgical outcomes in neurosurgery.
Area Of Science
- Neurosurgery
- Surgical Oncology
- Medical Imaging
Background
- Schwannomas often involve and compress adjacent neural structures.
- Second Window Indocyanine Green (SWIG) utilizes near-infrared (NIR) light and indocyanine green (ICG) for intraoperative tumor visualization.
- SWIG offers potential for enhanced tumor resection while preserving critical nerves.
Purpose Of The Study
- To demonstrate the utility of SWIG in the surgical resection of cranial nerve schwannomas.
- To evaluate the effectiveness of SWIG in guiding tumor removal and nerve sparing.
Main Methods
- Three patients with trigeminal, vestibular, and vagus nerve schwannomas underwent SWIG-guided resection.
- Near-infrared visualization was intermittently employed to guide tumor resection.
- Signal-to-background ratio (SBR) was calculated to quantify fluorescence intensity.
Main Results
- All patients achieved total or near-total resection with symptom relief and no recurrence at six months.
- The average SBR was 3.79, indicating effective tumor visualization.
- ICG was administered at 5.0 mg/kg, 24 hours prior to surgery.
Conclusions
- This case series is the first to report SWIG use for trigeminal and vagus nerve schwannoma resection.
- SWIG may be applicable for visualizing various brain tumors, including all schwannomas.
- Optimal preoperative ICG infusion timing is crucial for effective SWIG imaging.
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