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Updated: Jun 29, 2025

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Surgical Heritage: You Had to Be There, Ross: The Comeback Kid
Magdi H Yacoub1, Maximiliaan L Notenboom2, Giovanni Melina3
1National Heart and Lung Institute, Imperial College London, London, United Kingdom; Heart Science Centre, Magdi Yacoub Institute, Harefield, United Kingdom.
Abstract:
Half a century after the first pulmonary autograft operation (Ross operation), performed in 1967 by Donald Ross in central London, there is a very strong conviction that the Ross operation is the best available valve substitute today, not only for children, but also for younger and older adults. The Ross operation has stimulated a lot of science to do with tissue-engineering and biology of heart valves, which is a promising avenue for the future. For one of us (M.Y.), it has certainly been a privilege to be associated with the comeback of the Ross operation.
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