Related Experiment Video
Updated: Aug 7, 2026
07:22
Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors
Published on: November 20, 2013
16.9K
Yb-TCPP metal-organic framework as fluorescence sensor for detecting tetracycline in milk
Ximan Zhang1, Yun Zhang1, Lina Zhao2
1School of Food Engineering, East University of Heilongjiang, Harbin, China.
Summary
A new fluorescence method effectively detects tetracycline (TC) contamination in milk. This Yb-TCPP metal-organic framework offers a sensitive and selective approach for monitoring this common milk pollutant.
Area of Science:
- Analytical Chemistry
- Materials Science
Background:
- Tetracycline (TC) is a prevalent organic pollutant in milk due to its veterinary use.
- TC contamination poses significant risks to human health.
- Current methods for in situ TC detection in milk are insufficient.
Purpose of the Study:
- To develop a highly sensitive and selective fluorescence method for detecting TC in milk.
- To utilize a novel metal-organic framework material for this detection.
Main Methods:
- Synthesis of Ytterbium-tetra(4-carboxyphenyl)porphyrin (Yb-TCPP) metal-organic framework.
- Development of a fluorescence-based detection assay for TC.
- Characterization of Yb-TCPP's fluorescence properties and TC detection performance.
Main Results:
- The Yb-TCPP material demonstrated high sensitivity and selectivity for TC detection.
- A high Stern-Volmer constant (KSV) of 12,310.88 M-1 was calculated.
- A low detection limit of 2.44 × 10-6 M was achieved, surpassing previous methods.
- Yb-TCPP exhibits near-infrared fluorescence, suitable for practical applications.
Conclusions:
- The developed Yb-TCPP fluorescence method provides an effective means for detecting TC in milk.
- This approach offers superior sensitivity and selectivity compared to existing methods.
- The near-infrared fluorescence property of Yb-TCPP holds promise for developing practical milk contamination detection products.
