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Illumination of understudied ciliary kinases

Raymond G Flax1, Peter Rosston1,2, Cecilia Rocha3

  • 1Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.

Frontiers in Molecular Biosciences
|March 25, 2024
PubMed
Summary

Kinases regulate cilia biology and are implicated in neurological diseases and cancer. This review highlights progress in understanding ciliary kinases and developing chemical inhibitors for these key cellular regulators.

Keywords:
cancerchemical probeciliaciliogenesisciliopathykinaseneurological disorderunderstudied

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