Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

2.7K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
2.7K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

440
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
440
Glaucoma: Overview01:25

Glaucoma: Overview

565
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
565
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

485
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
485
Influence of Earth's Curvature and Atmospheric Refraction on Leveling01:26

Influence of Earth's Curvature and Atmospheric Refraction on Leveling

92
During leveling, the Earth's curvature and atmospheric refraction introduce deviations in the line of sight from a true horizontal reference. When the line of sight is leveled, it remains perpendicular to the plumb line only at a single point. Beyond this, it deviates due to the Earth’s curvature, represented by the correction C. For a sight distance D, the deviation can be derived using the relationship:This relationship shows that the deviation increases quadratically with distance.
92

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early nutritional consultation after emergency department MNA-SF assessment in hospitalized malnourished older adults.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
Same author

Risks and Familial Coaggregation of Autism Spectrum Disorder Among First-Degree Relatives of Individuals With Colorectal Cancer.

Psychiatry investigation·2026
Same author

Capacity-Responsive COVID-19 Testing Performance in Emergency Departments: Turnaround Time Thresholds for Lateral Flow Assay and Polymerase Chain Reaction Strategies.

Prehospital and disaster medicine·2026
Same author

Predictors of One-Year Mortality in Hospitalized Patients with Splenic Infarction: Survival Analysis of a Retrospective Cohort in Taiwan.

International journal of medical sciences·2026
Same author

Multi-Site Hymenoptera Stings Mark a High-Risk Subgroup in the Emergency Department.

The Kaohsiung journal of medical sciences·2026
Same author

Prognostic Factors for Mortality in Patients with Pyogenic Liver Abscess: A Systematic Review and Meta-Analysis.

International journal of medical sciences·2026
Same journal

Associations between visual skills and serve reception performance in elite male volleyball outside hitters.

Frontiers in physiology·2026
Same journal

Neuromuscular performance of the glenohumeral joint in young female tennis players: a cross-sectional study.

Frontiers in physiology·2026
Same journal

The myofascial rheostat: hyaluronan molecular weight dynamics and purinergic signalling as a physiological feedback system.

Frontiers in physiology·2026
Same journal

Effects of aquatic exercise on pain and physical function in overweight/obese patients with lower limb osteoarthritis: a systematic review and meta-analysis.

Frontiers in physiology·2026
Same journal

Effects of plyometric training on different surfaces on lower-limb power, dynamic balance, and agility in male collegiate tennis players.

Frontiers in physiology·2026
Same journal

Integrated serum metabolomics reveals severity-associated exploratory metabolic signatures in burn patients.

Frontiers in physiology·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.6K

High myopia at high altitudes.

Ta-Wei Wang1, Ming-Kun Huang2,3,4, Chih-Chun Hsu5

  • 1Department of Emergency Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.

Frontiers in Physiology
|March 25, 2024
PubMed
Summary
This summary is machine-generated.

Changes in optic nerve sheath diameter (ONSD) at moderate altitudes can predict acute mountain sickness (AMS) symptoms in trekkers. High myopia may affect ocular responses during high-altitude hiking.

Keywords:
acute mountain sicknesshigh altitudeshigh myopiaintraocular pressureoptic nerve sheath diameter

More Related Videos

Inducement and Evaluation of a Murine Model of Experimental Myopia
07:20

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

9.9K
Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

425

Related Experiment Videos

Last Updated: Jun 29, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.6K
Inducement and Evaluation of a Murine Model of Experimental Myopia
07:20

Inducement and Evaluation of a Murine Model of Experimental Myopia

Published on: January 22, 2019

9.9K
Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

425

Area of Science:

  • Ophthalmology
  • Altitude Physiology
  • High-Altitude Medicine

Background:

  • Optic nerve sheath diameter (ONSD) increases at high altitudes, correlating with acute mountain sickness (AMS).
  • High altitude exposure impacts intraocular pressure (IOP), but ocular responses in myopic trekkers are understudied.
  • High myopia (HM) may influence physiological adaptations to hypobaric hypoxia.

Purpose of the Study:

  • To investigate changes in ONSD and IOP in trekkers with and without high myopia (HM) during a high-altitude trek.
  • To determine if these ocular changes can predict AMS symptoms.
  • To explore the impact of HM on ocular physiological responses at altitude.

Main Methods:

  • A 3-day trek of Xue Mountain involving 9 participants with HM and 18 without HM.
  • Measurement of ONSD and IOP before and during the trek.
  • Assessment of AMS symptoms using questionnaires.

Main Results:

  • ONSD significantly increased in both HM and non-HM groups at 1,700m.
  • IOP was higher in the HM group at 3,150m.
  • Fractional ONSD changes at 1,700m correlated with AMS development (r=0.448, p=0.019) and headache (r=0.542, p=0.004).
  • ROC analysis showed ONSD fractional changes effectively predicted AMS (AUC=0.859) and headache (AUC=0.803).

Conclusions:

  • ONSD changes at moderate altitudes can predict AMS symptoms.
  • HM may influence ocular accommodation and aqueous humor regulation at high altitudes.
  • Monitoring ONSD may aid in predicting and managing AMS in trekkers.