Diabetic Markers, Five Years after Bariatric Surgery
Zahra Behrooznia1, Ali Jangjoo2, Farid Qoorchi Moheb Seraj3
1Department of Internal Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Middle East Journal of Digestive Diseases
|March 25, 2024
Summary
Bariatric surgery significantly improves diabetic markers and reduces medication needs in obese patients with diabetes over five years. However, dyslipidemia remains a concern, highlighting the need for continued management.
Area of Science:
- Endocrinology
- Metabolic Surgery
- Obesity Medicine
Background:
- Bariatric surgery is a key intervention for obesity and associated comorbidities such as diabetes mellitus.
- Long-term effects of bariatric procedures on metabolic health markers require further investigation.
Purpose of the Study:
- To evaluate the 5-year impact of bariatric surgery on diabetic and lipid markers in patients with diabetes mellitus.
- To assess changes in antidiabetic medication requirements post-surgery.
Main Methods:
- Retrospective analysis of 34 diabetic patients undergoing bariatric surgery (2016-2017).
- Comparison of diabetic markers (glucose, lipid profile) and medication use before and 5 years after surgery.
- Evaluation of Roux-en-Y gastric bypass (RYGB), one anastomosis gastric bypass (OAGB), and sleeve gastrectomy (SG) outcomes.
Main Results:
- Significant reduction in serum diabetic markers (P=0.001) and oral antidiabetic medication demand (P=0.006).
- Increase in high-density lipoprotein and total cholesterol levels; non-significant reduction in low-density lipoprotein.
- No significant reduction in insulin injection requirements (P=0.099).
Conclusions:
- Bariatric surgery demonstrates favorable long-term outcomes for diabetic patients, improving glycemic control.
- Dyslipidemia persists as a significant concern post-bariatric surgery, necessitating ongoing management strategies.
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