Severity of Coronary Artery Disease by Friesinger Score Among Women With Acute Coronary Syndrome in a Tertiary Care...

Area of Science:

• Cardiology
• Women's Health
• Medical Research

Background:

• Menopause significantly increases coronary artery disease (CAD) risk in women due to hormonal changes.
• Postmenopausal women often present with more advanced CAD and comorbidities.
• Limited data exists on angiographic severity differences in acute coronary syndrome (ACS) between premenopausal and postmenopausal women.

Purpose of the Study:

• To evaluate the utility of the Friesinger score in assessing CAD severity in premenopausal versus postmenopausal women with ACS.
• To compare angiographic findings and clinical data between these two groups.

Main Methods:

• A cross-sectional observational study included 145 female patients diagnosed with ACS.
• Patients were divided into two groups: premenopausal (Group I) and postmenopausal (Group II).
• Coronary angiographic features, assessed using the Friesinger score, were compared between groups.

Main Results:

• Postmenopausal ACS patients were significantly older (57.23 ± 7.45 years) than premenopausal patients (41.53 ± 5.45 years).
• The prevalence of normal coronary angiography and single-vessel disease was higher in premenopausal women.
• Triple-vessel disease was more prevalent in postmenopausal women, with a significantly higher Friesinger score (indicating greater severity).

Conclusions:

• Premenopausal women with ACS more frequently showed normal coronary angiography or single-vessel disease.
• Postmenopausal women with ACS demonstrated more severe CAD, characterized by a higher prevalence of triple-vessel disease.
• The Friesinger score confirmed greater CAD severity in the postmenopausal group compared to the premenopausal group.