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Related Concept Videos

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Related Experiment Video

Updated: Jun 29, 2025

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
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Implementation of a prehospital whole blood program: Lessons learned.

Matthew J Levy1,2,3, Eric M Garfinkel1,2, Robert May2

  • 1Department of Emergency Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA.

Journal of the American College of Emergency Physicians Open
|March 25, 2024
PubMed
Summary
This summary is machine-generated.

Early administration of blood products by Emergency Medical Services (EMS) significantly improves outcomes for patients with hemorrhagic shock. Implementing prehospital blood programs, guided by best practices, enhances resuscitation and patient survival.

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Area of Science:

  • Emergency Medicine
  • Trauma Resuscitation
  • Blood Transfusion Services

Background:

  • Hemorrhagic shock requires timely intervention to prevent organ damage.
  • Prehospital blood programs offer critical resuscitation capabilities.
  • Successful programs necessitate careful planning, safeguards, training, and resource management.

Purpose of the Study:

  • To describe the operational experience of Maryland's first prehospital ground-based low-titer O-positive whole blood program.
  • To share lessons learned for establishing and managing similar prehospital blood transfusion initiatives.
  • To inform other EMS systems on best practices for prehospital blood administration.

Main Methods:

  • Implementation of a prehospital blood program based on a four-pillar model (Yazer et al., 2022).
  • Focus on product rationale, storage and transport, transfusion criteria and personnel, and documentation.
  • Operational experience and lessons learned from Maryland's program.

Main Results:

  • Successful establishment and operation of Maryland's inaugural prehospital ground-based low-titer O-positive whole blood program.
  • Demonstrated feasibility of implementing prehospital blood transfusion protocols.
  • Identified key factors for successful program implementation and resource stewardship.

Conclusions:

  • Prehospital blood programs are vital for improving outcomes in patients with hemorrhagic shock.
  • Adherence to established best practices is crucial for program success.
  • The Maryland experience provides a valuable model for other EMS systems developing prehospital blood programs.