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Updated: Jun 29, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Heterochronous multiple primary prostate cancer and lymphoma: A case report
Jin-Long Liang1, Yu-Qing Bu1, Li-Li Peng1
1Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China.
Background:
Multiple primary malignant tumors (MPMTs) are rare type of cancer, especially when solid tumors are the first and lymphoma is the second primary malignancy. We report a patient with heterochronous MPMTs consisting of prostate cancer and rectal diffuse large B-cell lymphoma (DLBCL).
Case Summary:
We report a 77-year-old male patient diagnosed with prostate cancer who was treated with radiation therapy and one year of endocrine therapy with bicalutamide (50 mg per day) and an extended-release implant of goserelin (1/28 d). Seven years later, rectal DLBCL with lung metastases was found.
Conclusion:
Although rare, the possibility of prostate cancer combined with a double primary cancer of DLBCL can provide a deeper understanding.

