Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Chromium- and Monolayer Graphene-Based Coating for THz-Assisted Atom Probe Tomography of Sol-Gel Silica Specimens.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2026
Same author

Antibacterial Activity of Solid-Supported Gold Nanorods Combined with Antimicrobial Peptides.

ACS applied bio materials·2026
Same author

Preparation of Microcapsules Using a Poly(2-(dimethylamino)ethyl methacrylate)-<i>b</i>-poly(benzyl methacrylate) Diblock Copolymer Emulsifier.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Role of Defects in Atom Probe Analysis of Sol-Gel Silica.

ACS omega·2025
Same author

Laser-Assisted Field Evaporation of Chromia with Deep Ultraviolet Laser Light.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2024
Same author

Photothermal Properties of Solid-Supported Gold Nanorods.

Nano letters·2024

Related Experiment Video

Updated: Jun 29, 2025

Atom Probe Tomography Analysis of Exsolved Mineral Phases
08:14

Atom Probe Tomography Analysis of Exsolved Mineral Phases

Published on: October 25, 2019

7.3K

Silica-embedded Gold Nanoparticles Analyzed by Atom Probe Tomography.

Gustav Eriksson1, Mats Hulander1, Mattias Thuvander2

  • 1Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Kemigården 4, SE-41296 Gothenburg, Sweden.

Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
|March 25, 2024
PubMed
Summary

This study introduces silica embedding for nanoparticle analysis using Atom Probe Tomography (APT). This method preserves nanoparticle hydration, enabling detailed characterization of their composition and surface ligands.

Keywords:
atom probe tomographygold nanoparticlessilica embeddingstabilizing ligands

More Related Videos

Processing of Bulk Nanocrystalline Metals at the US Army Research Laboratory
08:58

Processing of Bulk Nanocrystalline Metals at the US Army Research Laboratory

Published on: March 7, 2018

9.4K
Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy
10:29

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy

Published on: February 5, 2017

12.7K

Related Experiment Videos

Last Updated: Jun 29, 2025

Atom Probe Tomography Analysis of Exsolved Mineral Phases
08:14

Atom Probe Tomography Analysis of Exsolved Mineral Phases

Published on: October 25, 2019

7.3K
Processing of Bulk Nanocrystalline Metals at the US Army Research Laboratory
08:58

Processing of Bulk Nanocrystalline Metals at the US Army Research Laboratory

Published on: March 7, 2018

9.4K
Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy
10:29

Studying Dynamic Processes of Nano-sized Objects in Liquid using Scanning Transmission Electron Microscopy

Published on: February 5, 2017

12.7K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Nanoparticles possess unique properties driving diverse applications.
  • Characterization of nanoparticles is essential for understanding their behavior.
  • Current Atom Probe Tomography (APT) sample preparation often alters nanoparticle environments.

Purpose of the Study:

  • To develop a novel silica embedding method for nanoparticle analysis via APT.
  • To enable the study of nanoparticles in their hydrated state.
  • To investigate the potential for analyzing nanoparticle composition and surface ligands.

Main Methods:

  • Gold nanoparticles were densely packed onto a surface via chemisorption.
  • The nanoparticle-covered surface was embedded in a silica film, replacing water.
  • The prepared samples were analyzed using Atom Probe Tomography (APT).

Main Results:

  • Silica embedding successfully created a suitable matrix for APT analysis of nanoparticles.
  • The method allowed for the study of nanoparticles in a hydrated state.
  • APT analysis revealed the silver content and distribution within the nanoparticles.
  • Sodium clusters, likely from citrate stabilizers, were observed on nanoparticle surfaces.

Conclusions:

  • Silica embedding is a viable technique for preparing hydrated nanoparticles for APT analysis.
  • This method facilitates the study of nanoparticle composition and surface chemistry.
  • The technique shows potential for investigating ligands on nanoparticles in their native hydrated environment.