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Updated: Aug 5, 2026

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
07:57

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin

Published on: August 25, 2022

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Reduced racial disparities among newborns with intraventricular hemorrhage

Sumaiya Sayeed1, Benjamin C Reeves1, Brianna C Theriault1

  • 1Department of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|March 25, 2024
PubMed

Insights

Race does not impact healthcare outcomes for newborns with intraventricular hemorrhage (IVH). This study found no significant differences in adverse events, length of stay, or total cost of admission based on race.

Area of Science:

  • Neonatal Medicine
  • Pediatric Neurology
  • Health Services Research

Background:

  • Intraventricular hemorrhage (IVH) in newborns can lead to severe complications, including neurological dysfunction, morbidity, and mortality.
  • Existing research on IVH disparities has focused on gender and weight, with limited investigation into the role of race.
  • Understanding racial influences is crucial for addressing healthcare inequities in neonatal care.

Purpose of the Study:

  • To investigate the impact of race on adverse event (AE) rates, length of stay (LOS), and total cost of admission in neonatal and infantile IVH patients.
  • To determine if race is an independent predictor of extended LOS or exorbitant healthcare costs.
  • To identify potential racial disparities in healthcare outcomes for infants with IVH.

Main Methods:

  • Utilized the 2016-2019 National Inpatient Sample database to identify newborns with IVH using ICD-10-CM codes.
  • Stratified patients based on race (White, African American, Hispanic, Other) and analyzed patient characteristics and inpatient outcomes.
  • Employed multivariate logistic regression analyses to assess the impact of race on extended LOS and exorbitant cost.

Main Results:

  • Analysis of 1435 patients revealed no significant differences in AE rates, mortality rates, mean LOS, or mean total cost of admission across racial groups.
  • While African American patients showed higher rates of necrotizing enterocolitis (NEC), this did not translate to differential overall outcomes.
  • Multivariate analysis confirmed that race was not a significant independent predictor of extended LOS or exorbitant cost.

Conclusions:

  • Race was not found to be associated with proxies of poor healthcare outcomes, such as prolonged LOS or excessive cost, in newborns with IVH.
  • These findings suggest that current healthcare delivery for IVH in newborns may not be significantly influenced by race.
  • Further research is recommended to validate these results and explore other potential factors influencing IVH outcomes.
Abstract

Keywords:
Intraventricular hemorrhageLength of stayNational Inpatient SampleNewbornsRace

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