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Updated: Jun 29, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
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Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

Published on: July 24, 2013

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Life expectancy and mental related burden of disease among people living with HIV/AIDS

Hanxi Zhang1,2, Zheng Li2, Peilong Li2

  • 1Beijing Ditan Hospital Capital Medical University, Beijing, People's Republic of China.

AIDS Care
|March 25, 2024
PubMed

Insights

Mental health issues significantly burden people living with HIV/AIDS (PLHIV). This study quantifies the disease burden from mental disorders in Chinese PLHIV, highlighting suicide

Area of Science:

  • Public Health
  • Epidemiology
  • Mental Health Research

Background:

  • Mental health problems represent a significant disease burden for people living with HIV/AIDS (PLHIV).
  • Understanding this burden is crucial for effective healthcare strategies in China.
  • Previous research has not fully quantified mental health's impact on PLHIV in mainland China.

Purpose of the Study:

  • To measure the disease burden attributable to mental disorders among people living with HIV/AIDS in mainland China.
  • To analyze the impact of mental health conditions on life expectancy and disability-adjusted life years (DALYs) in this population.
  • To provide localized data for targeted interventions.

Main Methods:

  • Utilized national HIV/AIDS case reporting system data.
  • Employed life-table methods to evaluate life expectancy (LE) and LE-eliminated suicide.
  • Calculated Years of Life Lost (YLLs) and Years Lived with Disability (YLDs) using depression symptom scales (CES-D).

Main Results:

  • Antiviral therapy has prolonged life expectancy for PLHIV.
  • Suicide accounted for the highest proportion of YLLs (5.46%) in the 15-24 age group.
  • The 25-34 age group exhibited the highest YLDs; males and heterosexual-infected PLHIV generally showed higher YLDs and YLLs.

Conclusions:

  • This study provides the first localized data on the disease burden of mental health problems among PLHIV in China.
  • Mental health interventions are critical for improving outcomes and quality of life for PLHIV.
  • Findings underscore the need for tailored mental health support based on age, sex, and transmission route.

Keywords:
HIVburden of diseasedepressionlife expectancysuicide

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