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Updated: Jun 29, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Life expectancy and mental related burden of disease among people living with HIV/AIDS
Hanxi Zhang1,2, Zheng Li2, Peilong Li2
1Beijing Ditan Hospital Capital Medical University, Beijing, People's Republic of China.
Mental health issues significantly burden people living with HIV/AIDS (PLHIV). This study quantifies the disease burden from mental disorders in Chinese PLHIV, highlighting suicide
Area of Science:
- Public Health
- Epidemiology
- Mental Health Research
Background:
- Mental health problems represent a significant disease burden for people living with HIV/AIDS (PLHIV).
- Understanding this burden is crucial for effective healthcare strategies in China.
- Previous research has not fully quantified mental health's impact on PLHIV in mainland China.
Purpose of the Study:
- To measure the disease burden attributable to mental disorders among people living with HIV/AIDS in mainland China.
- To analyze the impact of mental health conditions on life expectancy and disability-adjusted life years (DALYs) in this population.
- To provide localized data for targeted interventions.
Main Methods:
- Utilized national HIV/AIDS case reporting system data.
- Employed life-table methods to evaluate life expectancy (LE) and LE-eliminated suicide.
- Calculated Years of Life Lost (YLLs) and Years Lived with Disability (YLDs) using depression symptom scales (CES-D).
Main Results:
- Antiviral therapy has prolonged life expectancy for PLHIV.
- Suicide accounted for the highest proportion of YLLs (5.46%) in the 15-24 age group.
- The 25-34 age group exhibited the highest YLDs; males and heterosexual-infected PLHIV generally showed higher YLDs and YLLs.
Conclusions:
- This study provides the first localized data on the disease burden of mental health problems among PLHIV in China.
- Mental health interventions are critical for improving outcomes and quality of life for PLHIV.
- Findings underscore the need for tailored mental health support based on age, sex, and transmission route.
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