Anti-IgLON5 Disease With Inaugural Bilateral Neuropapillitis

Sarah Demortiere1, Bastien Joubert1, Marie Benaiteau1

  • 1From the Department of Neurology (S.D., F.H., C.B., A.R., B.A., A.M., J.P.), Centre Hospitalier la Timone, Aix Marseille Univ; French Reference Center on Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis (B.J., M.B., B.A., A.M., J.P.); Department of Neurology (B.J., M.B., B.A., A.M., J.P.), Centre Hospitalier Lyon Sud, Hospices Civils de Lyon; Department of Ophtalmology (N.S., B.A., A.M., J.P.), Centre Hospitalier la Timone, Aix Marseille Univ; Departement of Medical Biology (V.D., B.A., A.M., J.P.), Centre Hospitalier Lyon Sud, Hospices Civils de Lyon; and Aix Marseille Univ (B.A., A.M., J.P.), CNRS, CRMBM, Marseille, France.

Neurology
|March 25, 2024
PubMed
Abstract

No abstract available in PubMed .

Related Concept Videos

Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Diphtheria01:28

Diphtheria

Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...