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Related Concept Videos

Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
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Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
Lipid Catabolism01:25

Lipid Catabolism

Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...

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Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate
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Encephalocraniocutaneous Lipomatosis: A Case Report.

Emelyn Zaworski1, Erin Gruber1, Andrew Regent-Smith2

  • 1From the Medical College of Wisconsin.

Annals of Plastic Surgery
|March 25, 2024
PubMed
Summary

Encephalocraniocutaneous lipomatosis (ECCL), a rare congenital syndrome, can be diagnosed by clinical criteria like nevus psiloliparus (NP). Early identification of NP is crucial for screening systemic involvement in infants.

Area of Science:

  • Genetics and rare diseases
  • Dermatology and neurology

Background:

  • Encephalocraniocutaneous lipomatosis (ECCL) is a rare congenital disorder, a subtype of oculoectodermal syndrome.

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  • ECCL is characterized by skin, eye, and central nervous system (CNS) anomalies, potentially linked to postzygotic mutations.
  • Nevus psiloliparus (NP), a hairless fatty nevus, is a key clinical diagnostic criterion for ECCL.