Increases in stress and adverse childhood experiences are associated with the co-occurrence of anxiety and depression in oncology patients
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View abstract on PubMed
Summary
This summary is machine-generated.This study identified three patient subgroups based on anxiety and depression levels during chemotherapy. Higher anxiety and depression correlated with increased stress and adverse childhood experiences, highlighting the need for mental health support.
Area Of Science
- Oncology
- Psychiatry
- Psychology
Background
- Anxiety and depression are common comorbidities in cancer patients undergoing chemotherapy.
- Understanding distinct patient profiles is crucial for tailored interventions.
- Previous research has not fully characterized joint anxiety and depression patterns in this population.
Purpose Of The Study
- To identify distinct subgroups of patients with joint anxiety and depression profiles during chemotherapy.
- To evaluate demographic, clinical, stress, resilience, and coping differences among these subgroups.
Main Methods
- A longitudinal study involving 1328 patients receiving chemotherapy.
- Latent profile analysis was used to identify joint anxiety and depression profiles over two chemotherapy cycles.
- Measures included state anxiety, depression, stress, resilience, coping, and adverse childhood experiences.
Main Results
- Three distinct patient profiles were identified: Low Anxiety/Low Depression (57.5%), Moderate Anxiety/Moderate Depression (33.7%), and High Anxiety/High Depression (8.8%).
- A dose-response relationship was observed between stress levels and the identified profiles.
- Patients in the higher anxiety and depression profiles reported more adverse childhood experiences.
Conclusions
- Distinct anxiety and depression profiles exist among chemotherapy patients.
- Higher levels of anxiety and depression are associated with increased stress and a history of adverse childhood experiences.
- Oncology providers should consider referrals for stress reduction, mental health, and social services to address these patient needs.
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