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Updated: Jun 18, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
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Addressing Disparities in Acute Stroke Management and Prognosis.

M Carter Denny1,2, Nicole Rosendale3,4, Nicole R Gonzales5

  • 1Department of Neurology Georgetown University School of Medicine Washington DC USA.

Journal of the American Heart Association
|March 26, 2024
PubMed
Summary
This summary is machine-generated.

Disparities in acute stroke care persist, impacting long-term outcomes. Implementation science offers strategies, like culturally tailored education and addressing provider bias, to improve stroke equity and reduce treatment delays for all populations.

Keywords:
disparitiesequityimplementation sciencestroke

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Area of Science:

  • Neurology
  • Public Health
  • Implementation Science

Background:

  • Abundant data show disparities in acute stroke management and prognosis.
  • Interventions to reduce these disparities are limited.
  • This report reviews disparities and implementation science opportunities in early stroke care.

Purpose of the Study:

  • Critically review the current landscape of disparities in acute stroke care.
  • Highlight opportunities to use implementation science to reduce disparities.
  • Focus on the early care continuum.

Main Methods:

  • Review of existing literature on stroke care disparities.
  • Analysis of interventions in prehospital and hospital settings.
  • Exploration of implementation science frameworks.

Main Results:

  • Prehospital interventions (multilevel education, mobile stroke units) show promise in reducing delays and improving access.
  • Hospital interventions addressing implicit bias and implementing stroke systems of care are crucial.
  • Disparities disproportionately affect Black and Hispanic populations, leading to worse long-term outcomes.

Conclusions:

  • Multilevel, culturally tailored education and mobile stroke units can improve prehospital stroke care equity.
  • Addressing healthcare provider implicit bias and implementing standardized stroke protocols are vital for hospital equity.
  • A learning health system approach is needed to translate evidence into practice and reduce stroke care disparities.