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Updated: Jun 29, 2025

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Effectiveness of allergen immunotherapy with house dust mite extract for pediatric bronchial asthma
Masaaki Hamada1, Keigo Saeki2, Ichiro Tanaka1
1Department of Pediatrics, Yao Municipal Hospital, Osaka, Japan.
Abstract:
Aim: We compared the effectiveness of rush subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) using standardized house dust mite (HDM) extract for pediatric bronchial asthma (BA). Methods: We followed the pediatric BA treatment score during 3 years of treatment. We assessed the median time to no longer requiring long-term control pharmacotherapy (LTCP) for BA (LTCP-free). We compared the outcomes after adjustment for confounding factors and propensity score matching. Results: Patients in the HDM SCIT group achieved the LTCP-free status significantly earlier than those in the HDM SLIT group after adjustment for confounding factors and propensity score matching. Conclusion: Patients treated for pediatric BA with rush HDM SCIT had earlier onset of therapeutic effects than those with HDM SLIT.
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