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Comparable Psychotropic Prescription Rates After Hospital Discharge Between Patients with COVID-19 and Those With
Yuna Takahashi1, Taisuke Yatomi2, Naohito Yamaguchi3
1Division of Drug Informatics, Keio University Faculty of Pharmacy, Tokyo, Japan.
Psychiatric symptoms after COVID-19 were not significantly different from other respiratory infections. Increased hospitalization severity was linked to higher psychotropic drug prescriptions in both COVID-19 and non-COVID patients.
Area of Science:
- Medical Research
- Infectious Diseases
- Psychiatry
Background:
- The specificity of psychiatric symptoms following coronavirus disease 2019 (COVID-19) recovery is not well-established.
- Understanding post-infection mental health outcomes is crucial for comprehensive patient care.
Purpose of the Study:
- To investigate whether psychiatric symptoms after COVID-19 recovery are specific to the illness.
- To compare the incidence of new psychotropic drug prescriptions between COVID-19 and non-COVID respiratory infection patients.
Main Methods:
- Retrospective analysis of inpatient data from Saiseikai-affiliated hospitals (2020-2022).
- Comparison of new psychotropic drug prescriptions post-discharge between COVID-19 and non-COVID groups.
- Utilized Diagnosis Procedure Combination and outpatient clinic data; employed chi-square/Fisher's exact tests and COX proportional-hazards models.
Main Results:
- Included 3,648 COVID-19 and 8,732 non-COVID patients; 5.6% of COVID-19 patients received psychotropic prescriptions.
- No significant difference in psychotropic prescription rates between COVID-19 and non-COVID groups.
- Increased hospitalization severity was significantly associated with higher psychotropic prescriptions (HR 1.83, p<0.001).
Conclusions:
- Psychiatric symptoms requiring psychotropic medication do not appear specific to COVID-19 compared to other respiratory infections.
- Close observation for psychiatric symptoms is recommended, particularly for patients with severe hospitalization, irrespective of COVID-19 status.
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