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  11. Correlation Of Shear-wave Elastography Stiffness And Apparent Diffusion Coefficient Values With Tumor Characteristics In Breast Cancer

Correlation of shear-wave elastography stiffness and apparent diffusion coefficient values with tumor characteristics in breast cancer

Mi-Ri Kwon1, Inyoung Youn1, Eun Sook Ko2

  • 1Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Scientific Reports
|March 27, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

Shear-wave elastography (SWE) and apparent diffusion coefficient (ADC) values in breast cancer are negatively correlated. Higher SWE values indicate larger tumor size, triple-negative subtype, and aggressive imaging features.

Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Breast cancer diagnosis relies on imaging techniques.
  • Shear-wave elastography (SWE) and apparent diffusion coefficient (ADC) are advanced MRI techniques.
  • Understanding their correlation can improve breast cancer characterization.

Purpose of the Study:

  • To investigate the correlation between SWE and ADC values in breast cancer.
  • To identify imaging and pathological characteristics associated with these values.

Main Methods:

  • Retrospective analysis of 91 breast cancer patients.
  • Pre-operative SWE and breast MRI were performed.
  • Correlation analysis between SWE, ADC values, and tumor characteristics.

Main Results:

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  • ADC values showed a negative correlation with mean and maximum SWE values (p < 0.002).
  • SWE positively correlated with tumor size (p < 0.001) and higher T stage.
  • Triple-negative breast cancer and aggressive imaging features (enhancement, vascularity, washout) showed higher SWE values.

Conclusions:

  • SWE stiffness and ADC values are negatively correlated in breast cancer.
  • SWE is a valuable tool for assessing tumor size, stage, and aggressiveness.
  • SWE may help differentiate aggressive breast cancer subtypes.