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Updated: Jun 29, 2025

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Emerging roles of prominin-1 (CD133) in the dynamics of plasma membrane architecture and cell signaling pathways in

Petr Pleskač1,2, Christine A Fargeas3,4, Renata Veselska1,2

  • 1Laboratory of Tumor Biology, Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.

Cellular & Molecular Biology Letters
|March 27, 2024
PubMed
Summary

Prominin-1 (CD133) is a cholesterol-binding protein crucial for stem cell identification. This review highlights its role in cell signaling, membrane dynamics, and tissue homeostasis, impacting cancer development.

Keywords:
CD133CancerCancer stem cellCell signalingCiliumExosomeLipid raftMicrovillusProminin-1Stem cell

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