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Published on: May 26, 2023
Subfoveal choroidal thickness in a general elderly population; Tehran geriatric eye study
Alireza Hashemi1, Payam Nabovati2, Abolghasem Mortazavi3
1Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Subfoveal choroidal thickness (SFCT) in elderly individuals varies with age, sex, pseudophakia, and cerebrovascular accident history. These factors are crucial for interpreting SFCT data in clinical and research settings.
Area of Science:
- Ophthalmology
- Gerontology
- Medical Imaging
Background:
- Subfoveal choroidal thickness (SFCT) is a key indicator of ocular health.
- Understanding SFCT distribution in elderly populations is vital for age-related eye disease research.
Purpose of the Study:
- To determine the distribution of SFCT in an elderly population.
- To identify demographic, ocular, and systemic factors associated with SFCT.
Main Methods:
- Population-based cross-sectional study (Tehran Geriatric Eye Study).
- Involved urban elderly individuals aged 60+.
- Choroidal imaging using Spectralis SD-OCT with enhanced depth imaging.
Main Results:
- Average SFCT was 265.3 ± 25.9 μm.
- Pseudophakia showed a direct relationship with SFCT (coefficient=5.69).
- Cerebrovascular accident history showed an inverse relationship with SFCT (coefficient=-4.77).
- Significant age-sex interaction: SFCT increased with age in men, decreased in women.
Conclusions:
- Established reference values for SFCT in the elderly.
- Age-sex interaction, pseudophakia, and CVA history are significant factors influencing SFCT.
- Recommends considering these factors for accurate SFCT data interpretation.
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