Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Global research trends in robotic surgery in andrology: a bibliometric and visualization analysis (2003-2025).

Journal of robotic surgery·2026

Same author

Correction: Factors affecting the need for ureteral catheterization in symptomatic pregnancy hydronephrosis.

International urology and nephrology·2026

Same author

Can the systemic immune-inflammation index be used to differentiate benign and malignant pathologies before transrectal ultrasound-guided prostate biopsy?

BMC urology·2025

Same author

Examination of the effect of spinal anesthesia informational video on anxiety level and postoperative analgesia in transurethral resection of prostate.

Frontiers in medicine·2025

Same author

Assessment of Sexual Dysfunction in Female Fibromyalgia Patients According to Golombok-Rust Sexual Satisfaction Scale.

Journal of sex & marital therapy·2025

Same author

The relationship between map scores and complications after standard percutaneous nephrolithotomy.

BMC urology·2024

Search research articles

Related Experiment Video

Updated: Jun 29, 2025

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

The Effect of Lymphovascular Invasion on Short-Term Tumor Recurrence and Progression in Stage T1 Bladder Cancer.

Osman Gercek¹, Melih Senkol¹, Veli Mert Yazar¹

¹Urology, Afyonkarahisar Health Sciences University, Afyonkarahisar, TUR.

|March 27, 2024

Summary

Lymphovascular invasion (LVI) in T1 high-grade bladder tumors significantly increases the risk of cancer progression after transurethral resection. Early radical cystectomy and neoadjuvant chemotherapy are recommended for patients with LVI.

Keywords:

bladder cancer disease progression lymphatic metastasis malignant tumor resection recurrence

More Related Videos

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8⁺ T Cells During LN Metastasis

Published on: January 26, 2024

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

Related Experiment Videos

Last Updated: Jun 29, 2025

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8⁺ T Cells During LN Metastasis

Published on: January 26, 2024

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

Area of Science:

Urology
Oncology
Pathology

Background:

Lymphovascular invasion (LVI) is a critical factor in tumor spread and metastasis.
The prognostic significance of LVI in transurethral resection of bladder tumors (TUR-BT) remains unclear.

Purpose of the Study:

To evaluate the impact of LVI on tumor progression and recurrence in patients with T1 high-grade bladder tumors following TUR-BT.

Main Methods:

Retrospective analysis of 58 patients with T1 high-grade bladder cancer who underwent TUR-BT without radical surgery.
Comparison of progression and recurrence rates at three months and one year, analyzing factors including LVI, tumor size, grade, and patient demographics.

Main Results:

LVI was detected in 15.5% of patients.
One-year progression to T2 tumor was significantly higher in patients with LVI (66.7%) compared to those without (10.2%) (p=0.001).
LVI was the sole significant predictor of one-year progression in logistic regression analysis (p=0.001).

Conclusions:

The presence of LVI in T1 high-grade bladder tumors is a significant predictor of increased tumor progression.
Early consideration of radical cystectomy and neoadjuvant chemotherapy for patients with LVI is warranted to improve disease management.