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Revolutionizing eye care: the game-changing applications of nano-antioxidants in ophthalmology

Yuhang Cheng1,2, Shundong Cai1,2, Han Wu2

  • 1Shen Zhen Research Institute of Xiamen University, Shenzhen 518057, China. chuchengchao@xmu.edu.cn.

Nanoscale
|March 27, 2024
PubMed

Insights

Antioxidant nanomedicine offers a promising approach to treating eye diseases caused by oxidative stress. This review explores nano-antioxidant applications for ocular surface and posterior eye conditions, overcoming traditional therapy limitations.

Area of Science:

  • Ophthalmology
  • Nanomedicine
  • Biomedical Engineering

Background:

  • Oxidative stress from reactive oxygen species (ROS) is implicated in eye disease development.
  • Traditional drug therapies have limitations in treating ophthalmic conditions.
  • Nanomedicine advancements offer new theranostic solutions for eye diseases.

Purpose of the Study:

  • To review the application of antioxidant nanomedicine in treating ocular diseases.
  • To classify eye diseases into ocular surface and posterior categories for targeted discussion.
  • To explore nano-antioxidant strategies for managing oxidative stress-related eye conditions.

Main Methods:

  • Literature review focusing on antioxidant nanomedicine in ophthalmology.
  • Classification of eye diseases based on affected area (ocular surface vs. posterior).
  • Analysis of nano-antioxidant applications, including nanocarriers, mechanisms, and therapeutic effects.

Main Results:

  • Nano-antioxidants show potential in treating various eye diseases driven by oxidative stress.
  • Specific examples of nanocarriers and their efficacy in ocular disease models are presented.
  • The review details the mechanisms of action and therapeutic outcomes of different nano-antioxidant strategies.

Conclusions:

  • Antioxidant nanomedicine represents a significant advancement in ophthalmic disease treatment.
  • Current research highlights progress and limitations, paving the way for future developments.
  • Further research is needed to optimize nanomedicine for enhanced safety and efficacy in ophthalmology.

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