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Published on: September 26, 2018
COVID-19 Associated Cardiovascular Disease-Risks, Prevention and Management: Heart at Risk Due to COVID-19
Andrew Kemerley1, Abhishek Gupta1, Mahesh Thirunavukkarasu1
1Department of Surgery, Molecular Cardiology and Angiogenesis Laboratory, University of Connecticut School of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT 06030, USA.
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) impacts the cardiovascular system, causing complications like myocarditis and cardiac failure. This review explores COVID-19
Area of Science:
- Cardiology
- Infectious Diseases
- Virology
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, has widespread health implications beyond the respiratory system.
- Cardiovascular complications are increasingly recognized in COVID-19 patients, affecting both adults and children.
- Pre-existing conditions like hypertension and diabetes exacerbate cardiovascular risks associated with COVID-19.
Purpose of the Study:
- To review the cardiovascular effects of SARS-CoV-2 infection.
- To discuss the mechanisms, clinical presentation, and diagnostic findings of COVID-19-related cardiovascular complications.
- To explore current and evolving treatment and prevention strategies for these complications.
Main Methods:
- Literature review of clinical outcomes, research findings, and case reports on SARS-CoV-2 and the cardiovascular system.
- Analysis of documented cardiovascular complications, including hyperinflammatory syndrome, myocarditis, and cardiac failure.
- Examination of diagnostic approaches and therapeutic interventions for managing cardiovascular manifestations of COVID-19.
Main Results:
- COVID-19 infection can lead to significant cardiovascular complications, such as myocarditis and heart failure, even in individuals without prior cardiovascular disease.
- Pediatric populations are susceptible to systemic complications like multisystem inflammatory syndrome in children (MIS-C).
- SARS-CoV-2 contributes to an inflammatory environment that negatively impacts cardiovascular health.
Conclusions:
- Understanding the mechanisms by which SARS-CoV-2 affects the cardiovascular system is crucial for effective patient management.
- Prompt diagnosis and tailored treatment strategies are essential for improving outcomes in patients with COVID-19-related cardiovascular complications.
- Further research is needed to fully elucidate the complex interplay between SARS-CoV-2 and cardiovascular physiology.
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