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Multifit: a flexible non-linear least squares regression program in BASIC.

A R Walmsley, A G Lowe

    Computer Methods and Programs in Biomedicine
    |November 1, 1985
    PubMed
    Summary
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    MULTIFIT is a BASIC program for microcomputers designed for non-linear least squares regression fitting. It simplifies the analysis of enzyme kinetic and pharmacokinetic data using customizable model equations.

    Area of Science:

    • Biophysics
    • Pharmacokinetics
    • Biochemistry

    Background:

    • Non-linear least squares regression is crucial for analyzing complex biological data.
    • Existing methods may lack flexibility for diverse model fitting.

    Purpose of the Study:

    • To develop a user-friendly microcomputer program for non-linear regression analysis.
    • To facilitate the fitting of enzyme kinetic and pharmacokinetic data to specific models.

    Main Methods:

    • Developed MULTIFIT, a BASIC program for microcomputers.
    • Implemented a procedure for inserting model equations with up to five parameters.
    • Supported up to 3 independent variables and 1 dependent variable.

    Main Results:

    Related Experiment Videos

  • MULTIFIT enables flexible non-linear least squares regression fitting.
  • The program allows for the generation of customized analysis programs.
  • Facilitates the analysis of enzyme kinetic and pharmacokinetic data.

    • Conclusions:

    • MULTIFIT provides an accessible tool for researchers needing to fit data to models.
    • The program's modular design enhances its applicability in various scientific fields.