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Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
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Left Ventricular Diastolic Dysfunction Is Associated with Poor Functional Outcomes after Endovascular Thrombectomy
Tony Y W Li1, Emma M S Toh2, Ying Ying Koh2
1Department of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.
Journal of Cardiovascular Development and Disease
|March 27, 2024
Summary
Left ventricular diastolic dysfunction (LVDD) is linked to worse functional recovery in acute ischemic stroke patients undergoing endovascular thrombectomy (ET). LVDD did not significantly impact in-hospital mortality in this study. Further research is recommended.
Area of Science:
- Cardiology
- Neurology
- Stroke Medicine
Background:
- Endovascular thrombectomy (ET) has improved outcomes for acute ischemic stroke (AIS) with large vessel occlusion (LVO).
- Left ventricular diastolic dysfunction (LVDD) is associated with poor prognosis in other cardiovascular conditions.
- The impact of LVDD on functional recovery after stroke remains unclear.
Purpose of the Study:
- To investigate the relationship between LVDD and clinical outcomes in patients with LVO AIS who underwent ET.
- To assess the association of LVDD with short-term mortality and functional recovery.
Main Methods:
- Retrospective cohort study of 261 LVO AIS patients who underwent ET.
- Correlation of LVDD with in-hospital mortality and modified Rankin Scale (mRS) score at 3 months (0-2 for good recovery).
Main Results:
- LVDD was present in 31.4% of patients.
- LVDD was associated with poorer functional recovery at 3 months (OR 2.18, 95% CI 1.04-4.54, p=0.038).
- LVDD was not significantly associated with increased in-hospital mortality (OR 2.18, 95% CI 0.60-7.99, p=0.240) after adjustment.
Conclusions:
- LVDD may indicate poorer outcomes in patients undergoing ET for LVO AIS, beyond traditional echocardiographic measures.
- Further investigation into the role of LVDD in stroke recovery is warranted.
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