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Using Multilayered Hydrogel Bioink in Three-Dimensional Bioprinting for Homogeneous Cell Distribution
Published on: May 2, 2020
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Recent Developments in Bio-Ink Formulations Using Marine-Derived Biomaterials for Three-Dimensional (3D) Bioprinting
1National Research Council of Canada, Aquatic and Crop Resource Development Research Centre, 1411 Oxford Street, Halifax, NS B3H 3Z1, Canada.
Marine Drugs
|March 27, 2024
Summary
Marine biomaterials offer sustainable, low-cost options for advanced 3D bioprinting bio-inks. This review explores their use, focusing on properties and applications in biomedical and pharmaceutical fields.
Area of Science:
- Biomaterials Science
- Additive Manufacturing
- Biotechnology
Background:
- 3D bioprinting is an additive manufacturing technology for creating complex 3D structures.
- It has potential applications in biomedical, pharmaceutical, and food industries.
- There is a need for sustainable, low-cost bio-inks with enhanced properties.
Purpose of the Study:
- To review the use of marine-derived biomaterials in 3D bioprinting bio-ink formulations.
- To highlight the potential of these renewable resources.
- To discuss challenges and future directions.
Main Methods:
- Literature review of 3D bioprinting processes.
- Analysis of marine-derived biomaterials (polysaccharides and proteins) for bio-ink applications.
- Focus on chitosan, glycosaminoglycans, alginate, carrageenan, collagen, and gelatin.
Main Results:
- Marine biomaterials are a viable and renewable source for bio-ink development.
- Specific marine materials like chitosan and alginate show promise.
- Properties such as mechanical strength, biocompatibility, and biodegradability are key considerations.
Conclusions:
- Marine-derived biomaterials are promising for developing advanced, sustainable 3D bioprinting inks.
- Further research is needed to overcome challenges in biomedical and pharmaceutical applications.
- Exploiting marine resources can lead to innovative bio-fabrication solutions.

