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Ethyl Cellulose-Core, OSA Starch-Shell Electrosprayed Microcapsules Enhance the Oxidative Stability of Loaded Fish
Elnaz Z Fallahasghari1, Peter Reimer Stubbe1, Ioannis S Chronakis1
1DTU-Food, Research Group for Food Production Engineering, Laboratory of Nano-BioScience, Technical University of Denmark, Henrik Dams Allé, B202, 2800 Kongens Lyngby, Denmark.
Nanomaterials (Basel, Switzerland)
|March 27, 2024
Summary
Coaxial electrospraying creates core-shell microcapsules that significantly improve cod liver oil (CLO) oxidative stability by 15-fold. Monoaxial electrospraying offers moderate 2.9-fold improvement, demonstrating the effectiveness of encapsulation for stabilizing fish oil.
Area of Science:
- Food Science and Technology
- Materials Science
- Chemical Engineering
Background:
- Cod liver oil (CLO) is rich in omega-3 fatty acids but prone to oxidation, limiting its shelf-life and efficacy.
- Microencapsulation is a key strategy to protect sensitive oils from degradation.
- Electrospraying offers a versatile method for microencapsulation, but different configurations may yield varied results.
Purpose of the Study:
- To investigate the encapsulation efficiency and oxidative stability of cod liver oil (CLO) using coaxial and monoaxial electrospraying techniques.
- To compare the structural properties and physical characteristics of microcapsules produced by the two methods.
- To evaluate the impact of microcapsule structure on the protection of CLO against oxidation.
Main Methods:
- Coaxial and monoaxial electrospraying were employed using ethyl cellulose and octenyl succinic anhydride (OSA)-modified starch as wall materials.
- Confocal microscopy, Raman spectroscopy, and atomic force microscopy were used to characterize microcapsule structure, oil location, surface adhesion, and mechanical properties.
- Differential scanning calorimetry (DSC) assessed the oxidative stability of encapsulated CLO compared to non-encapsulated oil.
- Finite element method (FEM) analyzed electric field strength distribution during electrospraying.
Main Results:
- Coaxial electrospraying produced core-shell (H-ECLO) microcapsules with CLO confined to the core, while monoaxial (ECLO) microcapsules showed CLO on the surface.
- H-ECLO microcapsules exhibited significantly lower surface adhesion and higher Young's modulus compared to ECLO microcapsules.
- H-ECLO microcapsules enhanced CLO oxidative stability by approximately 15 times, whereas ECLO microcapsules provided a 2.9-fold enhancement.
- Coaxial electrospraying generated a more favorable electric field distribution for microcapsule formation.
Conclusions:
- The coaxial electrospraying technique effectively creates a core-shell structure that significantly improves the oxidative stability of cod liver oil.
- Preventing oil presence on the microcapsule surface is crucial for maximizing oxidative protection.
- Electrospraying parameters and configuration play a vital role in determining the physical properties and protective capabilities of microcapsules.
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