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Types of Toxins01:36

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Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
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Diagnostic Necropsy and Selected Tissue and Sample Collection in Rats and Mice
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Editorial "Special Issue Clinical and Post Mortem Toxicology".

Eric J F Franssen1

  • 1Department of Clinical Pharmacy, OLVG Hospital, 1091 AC Amsterdam, The Netherlands.

Toxics
|March 27, 2024
PubMed
Summary

This Special Issue focuses on detecting recreational and novel psychoactive drug exposure and intoxications. It highlights challenges in identifying these substances for improved public health and safety.

Area of Science:

  • Forensic Toxicology
  • Analytical Chemistry
  • Clinical Chemistry

Background:

  • Growing prevalence of recreational and novel psychoactive drugs (NPS) poses significant public health challenges.
  • Existing detection methods often struggle with the rapid emergence and structural diversity of NPS.
  • Accurate identification of drug exposure and intoxication is crucial for timely medical intervention and legal proceedings.

Discussion:

  • Exploration of advanced analytical techniques for sensitive and specific detection of a wide range of psychoactive substances.
  • Addressing the complexities of matrix effects and metabolite identification in biological samples.
  • Discussing the need for standardized protocols and reference materials for reliable drug testing.

Key Insights:

  • Development of innovative methodologies for detecting emerging recreational drugs and NPS.

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  • Improved understanding of the toxicological profiles and clinical manifestations of NPS intoxication.
  • Highlighting the importance of interdisciplinary collaboration between forensic scientists, clinicians, and toxicologists.

    • Outlook:

    • Future directions in developing rapid, point-of-care testing for drug screening.
    • Potential for utilizing artificial intelligence and machine learning in identifying unknown substances.
    • Anticipating the need for continuous adaptation of detection strategies to combat evolving drug trends.