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Updated: Jun 29, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Brain Abscess Secondary to Streptococcus Intermedius Following an EGD with Biopsy in a Patient with Eosinophilic
N Begum Ozturk1, Tatjana Blazin1, Aparna Hariharan2
1Department of Internal Medicine, Beaumont Hospital, Royal Oak, Michigan.
Abstract:
Brain abscess is a rare complication of esophagogastro- duodenoscopy (EGD) with few reported cases in the literature. In this report, we discuss a patient presenting with altered mental status, headache, and dysarthria due to brain abscess caused by S. intermedius shortly after an EGD with an esophageal biopsy showing a new diagnosis of eosinophilic esophagitis. We highlight the rare association of EGD and brain abscess, and discuss the importance of prompt diagnosis and treatment.
Insights
Brain abscess is a rare complication following esophagogastroduodenoscopy (EGD). This case highlights Streptococcus intermedius causing a brain abscess after EGD and esophageal biopsy for eosinophilic esophagitis.
Area of Science:
- Neurology
- Gastroenterology
- Infectious Diseases
Background:
- Brain abscess is an uncommon complication of esophagogastroduodenoscopy (EGD).
- Reported cases linking EGD to brain abscess are scarce in medical literature.
- Esophagogastroduodenoscopy involves procedures like esophageal biopsy which can potentially lead to complications.
Purpose of the Study:
- To report a rare case of brain abscess following EGD.
- To highlight the association between EGD and brain abscess formation.
- To emphasize the need for timely diagnosis and management of brain abscess post-EGD.
Main Methods:
- Case report detailing a patient's clinical presentation and diagnostic process.
- Review of relevant literature on EGD-associated brain abscesses.
- Microbiological identification of the causative agent, Streptococcus intermedius.
Main Results:
- A patient developed a brain abscess caused by S. intermedius shortly after undergoing EGD with esophageal biopsy.
- The patient presented with neurological symptoms including altered mental status, headache, and dysarthria.
- The esophageal biopsy revealed a new diagnosis of eosinophilic esophagitis.
Conclusions:
- Esophagogastroduodenoscopy, particularly with biopsy, can rarely lead to brain abscess.
- Prompt recognition and treatment of brain abscess are crucial for favorable outcomes.
- This case underscores the importance of considering brain abscess in patients with neurological symptoms post-EGD.
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