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68 Ga-FAPI PET/CT in an Interesting Case of Metastatic Pulmonary Meningioma
Priyavrat Purohit1, Bhagwant Rai Mittal1, Rajender Kumar1
1From the Departments of Nuclear Medicine.
Abstract:
Meningiomas are one of the major primary CNS tumors. Most meningiomas are benign, but rarely, these metastasize to distant organs, the lungs being the commonest site of metastasis. 18 F-FDG PET/CT has been used to evaluate metastatic pulmonary meningioma. However, 68 Ga-FAPI PET/CT has not yet been evaluated. The present case highlights the 68 Ga-FAPI uptake in metastatic pulmonary meningioma in a postoperated case of left tentorial meningioma presenting with lung masses. Image-guided biopsy from the lung mass was consistent with metastatic meningioma.
Insights
This study shows that 68 Ga-FAPI PET/CT can detect metastatic pulmonary meningioma, a rare complication of brain tumors. This imaging technique offers a new option for evaluating lung metastases from meningiomas.
Area of Science:
- Neuro-oncology
- Nuclear Medicine
- Radiology
Background:
- Meningiomas are primary central nervous system (CNS) tumors, typically benign.
- Rarely, meningiomas can metastasize to distant sites, most commonly the lungs.
- 18F-FDG PET/CT is established for evaluating pulmonary meningioma metastases.
Observation:
- A patient with a history of left tentorial meningioma presented with lung masses post-surgery.
- The diagnostic utility of 68Ga-FAPI PET/CT for metastatic pulmonary meningioma had not been previously evaluated.
- The case involved assessing metastatic pulmonary meningioma using 68Ga-FAPI PET/CT.
Findings:
- The study observed significant 68Ga-FAPI uptake in the metastatic pulmonary meningioma.
- Image-guided biopsy confirmed the lung masses were metastatic meningioma.
- This highlights the potential of 68Ga-FAPI PET/CT in this rare oncological scenario.
Implications:
- 68Ga-FAPI PET/CT demonstrates potential as a diagnostic tool for metastatic pulmonary meningioma.
- This imaging approach may offer an alternative or complementary method to 18F-FDG PET/CT.
- Further research is warranted to establish the role of 68Ga-FAPI PET/CT in managing metastatic meningioma.
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