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Updated: Jun 29, 2025

Assessment and Communication for People with Disorders of Consciousness
Published on: August 1, 2017
The Constrained Disorder Principle May Account for Consciousness
Tal Sigawi1, Omer Hamtzany1, Josef Daniel Shakargy1
1Department of Medicine, Hadassah Medical Center, Faculty of Medicine, Hebrew University, Jerusalem IL12000, Israel.
Abstract:
There is still controversy surrounding the definition and mechanisms of consciousness. The constrained disorder principle (CDP) defines complex systems by their dynamic borders, limiting their inherent disorder. In line with the CDP, the brain exhibits a disorder bounded by dynamic borders essential for proper function, efficient energy use, and life support under continuous perturbations. The brain's inherent variability contributes to its adaptability and flexibility. Neuronal signal variability challenges the association of brain structures with consciousness and methods for assessing consciousness. The present paper discusses some theories about consciousness, emphasizing their failure to explain the brain's variability. This paper describes how the CDP accounts for consciousness's variability, complexity, entropy, and uncertainty. Using newly developed second-generation artificial intelligence systems, we describe how CDP-based platforms may improve disorders of consciousness (DoC) by accounting for consciousness variability, complexity, entropy, and uncertainty. This platform could be used to improve response to current interventions and develop new therapeutic regimens for patients with DoC in future studies.
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