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Updated: Jun 29, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Chemistry of Polythiols and Their Industrial Applications
Seung-Mo Hong1,2, Oh Young Kim1, Seok-Ho Hwang1
1Department of Polymer Science & Engineering, Dankook University, Yongin 16890, Republic of Korea.
Abstract:
Thiols can react with readily available organic substrates under benign conditions, making them suitable for use in chemical, biological, physical, and materials and engineering research areas. In particular, the highly efficient thiol-based click reaction includes the reaction of radicals with electron-rich enes, Michael addition with electron-poor enes, carbonyl addition with isocyanate SN2 ring opening with epoxies, and SN2 nucleophilic substitution with halogens. This mini review provides insights into emerging venues for their industrial applications, especially for the applications of thiol-ene, thiol-isocyanate, and thiol-epoxy reactions, highlighting a brief chemistry of thiols as well as various approaches to polythiol synthesis.
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