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Special Issue "COVID-19 Coagulopathy: Advances on Pathophysiology and Therapies"

Eliza Russu1,2, Emil-Marian Arbănaşi1,2,3,4, Alexandru Șchiopu5,6,7

  • 1Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania.

International Journal of Molecular Sciences
|March 28, 2024
PubMed

Insights

This special issue explores the complex mechanisms of COVID-19 coagulopathy, a serious complication of SARS-CoV-2 infection. Understanding these changes is crucial for developing effective therapeutic strategies against this challenging disease.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Pathophysiology

Background:

  • COVID-19 coagulopathy involves significant alterations in blood coagulation.
  • SARS-CoV-2 infection presents a complex challenge across medical specialties due to its impact on hemostasis.
  • This special issue addresses the need for a deeper understanding of these coagulation changes.

Discussion:

  • Investigating the intricate mechanisms behind COVID-19-associated coagulopathy.
  • Analyzing the multifaceted impact of SARS-CoV-2 on the coagulation cascade.
  • Bridging the gap between mechanistic understanding and clinical management of thrombotic complications.

Key Insights:

  • Elucidating the specific pathways through which SARS-CoV-2 disrupts normal coagulation.
  • Identifying key biomarkers for predicting and monitoring coagulopathy in COVID-19 patients.
  • Highlighting the heterogeneity of coagulation disorders in SARS-CoV-2 infection.

Outlook:

  • Developing targeted anticoagulant and anti-thrombotic therapies for COVID-19.
  • Improving patient outcomes by managing COVID-19 coagulopathy effectively.
  • Fostering interdisciplinary collaboration for comprehensive patient care.

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