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Breast Metastasis From Colorectal Carcinoma Identified by Gene Assay: Case Report and Review of Literature
Sugam Gouli1, Ansu Karki2, Jeffery Allerton3
1Hospital Medicine, Rochester Regional Health, New York, USA.
Cureus
|March 28, 2024
Summary
Metastatic colon cancer to the breast is rare and difficult to diagnose. Gene expression assays can identify the colon as the primary cancer site when immunohistochemistry is inconclusive.
Area of Science:
- Oncology
- Pathology
Background:
- Colon cancer metastasis to the breast is an uncommon clinical presentation associated with a poor prognosis.
- Immunohistochemistry (IHC) is typically used to identify the primary tumor site but can be non-conclusive in metastatic cases.
- Accurate primary tumor site diagnosis is crucial for effective treatment planning.

