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Updated: Jun 29, 2025

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Patterning of Microorganisms and Microparticles through Sequential Capillarity-assisted Assembly
Published on: November 4, 2021
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Progress in the Synthesis of Colloidal Machines
Nicolle S Jackson1, Samira Munkaila1, Lasya Damaraju1
1Molecular Design Institute and Department of Chemistry, New York University, New York, New York 10003, United States.
Summary
Dynamic colloids are key to building colloidal machines, bridging scales from nano to micro. Developing synthetic combinatorial design spaces is crucial for advancing this emerging field.
Area of Science:
- Colloidal science
- Materials science
- Nanotechnology
- Robotics
Background:
- Colloidal science has developed anisotropic subunits for assembling static and dynamic structures.
- Dynamic colloids are subunits capable of action in response to stimuli.
- Colloidal machines represent an emerging subfield, distinct from traditional self-assembly.
Purpose of the Study:
- To present the current state of colloidal science in the development of colloidal machines.
- To highlight the potential of dynamic colloids as building blocks for machines.
- To identify key challenges and future directions in the field.
Main Methods:
- Utilizing anisotropic and dynamic colloidal subunits for assembly.
- Viewing dynamic colloids as access points to colloidal machines.
- Comparing bottom-up fabrication of dynamic colloids with top-down methods for microscale machines.
Main Results:
- Colloidal machines (100 nm to 10 μm) are proposed as the next frontier in machine miniaturization.
- Dynamic assemblies offer unique environmental interaction capabilities compared to static assemblies.
- Current colloidal machines consist of single-composition dynamic subunits; future machines require multiple dynamic components.
Conclusions:
- The development of colloidal machines bridges the gap between nano, micro, and biological machinery.
- Repurposing existing dynamic particles is a viable strategy for creating colloidal machine components.
- Synthetic combinatorial design spaces are essential for realizing complex colloidal machines.
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