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[Prediction of CRISPR/Cas9 off-target activity using multi-scale convolutional neural network].

Huanzeng Xie1, Lingze Huang1, Ye Luo1

  • 1College of Engineering, Shantou University, Shantou 515063, Guangdong, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|March 28, 2024
PubMed
Summary

This study introduces CnnCRISPR, a novel deep learning method for predicting clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 9 (CRISPR/Cas9) gene editing off-target effects, improving accuracy and safety.

Keywords:
CRISPR/Cas9multi-scale convolutional neural networkoff-target effects

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