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Steven-Jonhson Syndrome in a Patient With Dengue Infection in Peru: A Case Report
Winny D Aparcana-Choque1, Yadira M Pisconti-Palacios1, Ivan Cordova-Tello1,2
1Universidad Privada San Juan Bautista, Lima, Perú.
Journal of Investigative Medicine High Impact Case Reports
|March 28, 2024
Summary
Stevens-Johnson syndrome, a severe skin reaction, can occur with certain epilepsy medications. This case highlights a potential link between arboviral diseases like dengue and Stevens-Johnson syndrome.
Area of Science:
- Dermatology
- Neurology
- Infectious Diseases
Background:
- Stevens-Johnson syndrome (SJS) is a rare, life-threatening condition affecting skin and mucous membranes.
- It is characterized by widespread blistering and detachment of the epidermis.
- Prompt treatment is crucial to reduce high mortality rates.
Observation:
- A 40-year-old male with epilepsy, treated with valproic acid and lamotrigine, developed SJS.
- The patient had a prior diagnosis of dengue fever.
- Clinical presentation included erythematous blisters, bleeding, and desquamation affecting 10% of the body surface.
Findings:
- The patient's SJS symptoms showed favorable progression with medical management.
- This case suggests a potential association between arboviral infections and SJS.
- Valproic acid and lamotrigine are known triggers for SJS.
Implications:
- Further research is warranted to explore the relationship between arboviral diseases and Stevens-Johnson syndrome.
- Clinicians should consider arboviral infections in the differential diagnosis of SJS, especially in endemic areas.
- Understanding this association may improve SJS diagnosis and management strategies.
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