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Related Concept Videos

Lung Capacity01:47

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.

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ISHLT Consensus Statement on Acute Lung Allograft Dysfunction (ALAD): Definition, Etiology, Diagnostic and Therapeutic Approaches, and Research Priorities.

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Related Experiment Video

Updated: Jun 28, 2026

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
06:55

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

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How do we expand the lung donor pool?

Bronwyn J Levvey1, Gregory I Snell

  • 1Lung Transplant Service, Department of Respiratory Medicine, Alfred Hospital, Melbourne, and Monash University, Melbourne, Australia.

Current Opinion in Pulmonary Medicine
|March 28, 2024
PubMed
Summary
This summary is machine-generated.

Innovations in lung transplantation are expanding the donor pool. Utilizing donation after circulatory death and older donors, alongside ex-vivo lung perfusion, improves lung availability for patients needing transplants.

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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

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Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
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Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

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Related Experiment Videos

Last Updated: Jun 28, 2026

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
06:55

Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP

Published on: February 14, 2022

1.6K
Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
09:54

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death

Published on: August 15, 2022

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Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

348

Area of Science:

  • Cardiovascular & Respiratory System Science
  • Transplantation Science
  • Regenerative Medicine

Background:

  • Lung transplantation is crucial for end-stage lung disease but limited by donor lung availability.
  • Clinical practice and scientific innovation are key to overcoming these limitations.

Purpose of the Study:

  • To review recent advancements in expanding the donor lung pool for transplantation.
  • To highlight innovations in clinical practice and scientific discovery.

Main Methods:

  • Review of studies on donation after circulatory death (DCD) lung donors.
  • Analysis of outcomes from older donors (>70 years).
  • Evaluation of strategies for utilizing Hepatitis C positive donor lungs and ex-vivo lung perfusion.

Main Results:

  • Successful lung transplants are increasing from DCD donors across all categories.
  • Donors over 70 years are yielding better-than-expected long-term outcomes.
  • Hepatitis C positive donor lungs are safely usable with postoperative antivirals; ex-vivo lung perfusion shows promise for donor management.

Conclusions:

  • Donor lungs are more robust than previously thought.
  • Clinical, scientific, and engineering innovations are significantly increasing the potential donor lung pool.
  • These advancements offer hope for improving lung transplantation accessibility.