Co-prevalence of arterial aneurysm location - a correlation analysis based on a retrospective cross-sectional

Daniel Körfer1, Samuel Kilian2, Caspar Grond-Ginsbach1

  • 1Department of Vascular and Endovascular Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Insights

Arterial aneurysm locations are not random. Paired artery aneurysms, like iliac or carotid, frequently co-occur. This finding impacts screening strategies for arterial aneurysms.

Area of Science:

  • Vascular Surgery
  • Medical Imaging
  • Epidemiology

Background:

  • Arterial aneurysms represent a significant vascular pathology.
  • Understanding the co-prevalence of aneurysm locations is crucial for risk stratification.
  • Previous studies have not systematically investigated the co-occurrence patterns of arterial aneurysms.

Purpose of the Study:

  • To systematically investigate the co-prevalence of arterial aneurysm locations.
  • To identify specific patterns and correlations in the occurrence of multiple aneurysms within patients.
  • To inform clinical practice and screening program development for arterial aneurysms.

Main Methods:

  • Retrospective, single-centre, cross-sectional observational study.
  • Inclusion of patients diagnosed with arterial aneurysms between 2006 and 2016.
  • Exclusion of patients with hereditary connective tissue disorders, inflammatory diseases, or non-true aneurysms.
  • Statistical analysis using correlation coefficients and Fisher's exact test to assess co-prevalence.

Main Results:

  • Analysis of 951 patients with at least two aneurysms revealed non-random co-prevalence.
  • Highest correlations observed in bilateral combinations of iliac, femoral, and popliteal arteries.
  • Lowest correlations found between abdominal aortic aneurysms and visceral, popliteal, or ascending aorta aneurysms.

Conclusions:

  • Aneurysm co-prevalence is significantly non-random, indicating specific location associations.
  • Findings suggest that the presence of an aneurysm in one location increases the likelihood of aneurysms in specific other locations.
  • These insights are vital for optimizing screening protocols and patient management strategies for arterial aneurysms.

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