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Aortic Regurgitation II: Clinical Features and Diagnostic Tests

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Updated: Jun 21, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Aortic Thrombus with Bilateral Renal Infarcts: A Case Report.

Lev Libet1

  • 1Kern Medical, Department of Emergency Medicine, Bakersfield, California.

Clinical Practice and Cases in Emergency Medicine
|March 28, 2024
PubMed
Summary

This case highlights a rare instance of bilateral renal infarction in a patient with protein C deficiency. Prompt imaging is crucial for high-risk patients presenting with symptoms suggestive of arterial thrombi.

Area of Science:

  • Nephrology
  • Hematology
  • Emergency Medicine

Background:

  • Hypercoagulable states increase risk for venous and arterial thrombi.
  • Protein C and S deficiencies are linked to venous thrombosis; arterial involvement is less common.
  • Renal artery thromboembolism can cause renal infarction, with bilateral cases being rare and severe.

Purpose of the Study:

  • To report a rare case of simultaneous bilateral renal infarction.
  • To emphasize the association between protein C deficiency and arterial thrombosis.
  • To highlight the importance of prompt diagnosis in at-risk patients.

Main Methods:

  • Case report of a 48-year-old male with known protein C deficiency.
  • Presentation with sudden abdominal pain.

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  • Diagnostic imaging via computed tomography angiogram of the abdomen.
  • Main Results:

    • Computed tomography angiogram revealed bilateral renal infarctions.
    • Patient experienced severe abdominal pain and developed acute kidney injury.
    • Conservative management was initiated; dialysis was not required.

    Conclusions:

    • This is the first reported case of bilateral renal infarction secondary to protein C and S deficiency in emergency medicine literature.
    • Early and definitive imaging is essential for patients at high risk for arterial thrombi presenting with suggestive symptoms.
    • This case underscores the potential for severe arterial complications in protein C deficiency.