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Rising Prevalence of Mild Chronic Gastritis in Children: A Single Center Experience
Rohit Josyabhatla1, Mary Lauren Wood2, Amber Gafur3
1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX, USA.
Objectives And Methods:
We analyzed upper endoscopic and histological findings in 3 cohorts of children undergoing upper gastrointestinal endoscopy over a 10-year period. Five hundred seventy-nine patients were identified, with 244 (42%), 199 (35%), and 136 (23%) in the 2011, 2015, and 2019 cohorts, respectively. The most common symptoms and signs were abdominal pain, vomiting, failure to thrive, and diarrhea.
Results:
The number of patients who had histological evidence of chronic gastritis increased from 2011 (n = 70, 29%) to 2015 (n = 106, 53%) and 2019 (n = 92, 68%; P < .001). The prevalence of "normal" endoscopic gastric findings was higher in controls (n = 247, 90%) compared to cases (n = 201, 76%; P < .001). There was a small but statistically significant difference in endoscopic esophageal grading (P = .008) over time, with lower grades being more prevalent in 2011 compared to 2015 (P = .026) and 2019 (P = .001). Crude comparisons of the predictors (sex, weight percentile, payor type, month of endoscopy, symptom duration, PPI exposure, and endoscopic stomach findings) yielded no difference between cases and controls.
Conclusions:
There has been a significant rise in the prevalence of mild chronic gastritis or non-specific gastritis over the last decade in our population.
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