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Updated: Jun 29, 2025

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Validation of the Comprehensive ICF Core Set for Multiple Sclerosis: A Turkish clinical perspective
Özge Ortabozkoyun1, Bilge Kesikburun1, Belma Füsun Köseoğlu1
1Department of Physical Therapy and Rehabilitation, Ankara Physical Therapy and Rehabilitation Hospital, Ankara, Türkiye.
The International Classification of Functioning, Disability and Health (ICF) Core Set for Multiple Sclerosis (MS) effectively measures disability and functioning in Turkish patients. It identifies key barriers and facilitators for targeted rehabilitation in MS care.
Area of Science:
- Rehabilitation Medicine
- Neurology
- Public Health
Background:
- Multiple Sclerosis (MS) significantly impacts individuals' functioning and disability.
- The International Classification of Functioning, Disability and Health (ICF) provides a standardized framework for assessing health and disability.
- The ICF Core Set for MS is designed to capture the most relevant ICF categories for individuals with MS.
Purpose of the Study:
- To evaluate the construct validity of the Comprehensive ICF Core Set for MS in a Turkish population.
- To identify the specific health domains affected by MS using ICF categories.
- To understand the facilitators and barriers to functioning and participation in individuals with MS.
Main Methods:
- A cohort of 150 individuals with MS was assessed using the Comprehensive ICF Core Set for MS.
- Spearman correlation coefficient was employed to assess the construct validity between ICF components and disease-specific/general measures.
- Data collection occurred between December 2011 and December 2012.
Main Results:
- Frequently reported impairments included pain, sleep, motivation, and muscle endurance (body functions), and brain, spinal cord, and lower extremity structures (body structures).
- Significant issues were found in 47 out of 53 activities and participation categories.
- Environmental factors presented both facilitators (23 categories) and barriers (12 categories).
- All ICF components demonstrated significant correlations with disease-specific and generic measures.
Conclusions:
- The Comprehensive ICF Core Set for MS exhibits construct validity in Turkish individuals.
- The ICF Core Set can identify major facilitators and barriers impacting functioning and disability in MS.
- This framework supports the development of targeted rehabilitation strategies for MS patients.
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