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Related Concept Videos

Protein Networks02:26

Protein Networks

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An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
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Protein-protein Interfaces02:04

Protein-protein Interfaces

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Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
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Proteomics01:33

Proteomics

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A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

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Protein Families02:47

Protein Families

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Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key...
15.3K
Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

10.8K
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
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Updated: Jun 29, 2025

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Retracted: Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine.

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    |March 29, 2024
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    Summary

    This article has been retracted. The retraction notice does not provide specific reasons but indicates the original publication is no longer considered valid scientific work.

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    Area of Science:

    • Scientific Publishing
    • Retraction Notices
    • Scholarly Communication

    Context:

    • The article identified by DOI: 10.1155/2022/2273648 has been retracted.
    • Retraction signifies that the scientific record associated with this publication is no longer considered valid.

    Purpose:

    • To formally announce the retraction of a specific scientific article.
    • To inform the scientific community and readers about the invalidation of the publication.

    Summary:

    • A retraction notice has been issued for the article with DOI: 10.1155/2022/2273648.
    • The reasons for retraction are not detailed in the provided notice.

    Impact:

    • Removes the retracted article from the scientific literature.
    • Maintains the integrity of the scientific record.
    • Alerts researchers to disregard the findings of the retracted publication.